Why a Global-PPS?

The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance (GLOBAL-PPS) is an ambitious project collecting data at global level to monitor rates of antimicrobial prescribing in hospitalised patients. The project is funded by bioMérieux.
This GLOBAL-PPS establishes a global network for point prevalence surveys and aims to include as many hospitals from as many countries from all continents. The proposed PPS will create global awareness about antibiotic use and resistance and will be instrumental in planning and supporting national and local stewardship interventions in a range of resource and geographical settings.

The data

Data collection implies conducting a “one day survey” including all admitted inpatients at 8 o’clock receiving an antimicrobial treatment. Next to antibiotics, also antifungals, antimycotics, antibiotics for the treatment of tuberculosis and antimalarials are surveyed. Data are collected on paper forms, and subsequently entered onto a database using the GLOBAL-PPS programme, a web-based application for data-entry, validation and reporting.
Essential data to collect are the patients’ age and gender, antimicrobial agent, dose per administration, number of doses per day, route of administration, anatomical site of infection or target for prophylaxis according to the list of provided reasons for treatment, indication for therapy (community versus hospital acquired infection or prophylaxis) and whether the treatment choice is determined by available microbiological or biomarker data. Denominator data are the number of admitted patients and the number of beds in each department.

Critical benefits for the hospitals?

GLOBAL-PPS will determine the variation in drug, dose and indications of antibiotic prescribing in hospitalised patients across all continents. The GLOBAL-PPS will provide a tool to:
  • Evaluate antimicrobial prescribing practices in hospitals,
  • Identify targets for quality improvement of antimicrobial prescribing,
  • Change practise and measure impact of interventions through repeated PPSs.

What kind of feedback is provided to you?

After final data-entry and validation, the hospital will be able to download a feedback which can be used for local communications and presentations. Hospital specific antimicrobial prevalence figures will be plotted against overall mean national and continental results. The feedback reports on several antibiotic quality indicators.

Next, hospitals can at any time extract their own data in an Excel file. These data can be analysed for own purposes. For results on the 2015 Global-PPS, click Dissemination; to view an anonymised feedback, click Documents.

Last but not least…

Data are completely anonymously entered online on the Global-PPS tool and safeguarded at the ESAC server of the University of Antwerp. The data remains the property of the hospital. bioMérieux has no access to these data, nor does the University of Antwerp disclose hospital names to any third party, including bioMérieux. Participation of hospitals and all fieldwork at the hospital level is done on a voluntary basis. The Global-PPS team encourages regional or country specific analysis led by a “local collaborating participant” or the “national or regional GLOBAL-PPS Participant”. A publication policy is available on request.

Foreseen timeline

Three surveys are available in 2019 to allow for investigating seasonal variation (January-April, May-August and Septem­ber-December 2019). There are currently no changes in the protocol compared to 2018.

Any hospital worldwide is welcome to participate.

Bigger hospitals who have participated to the 2015, 2017 or 2018 Global-PPS are able to participate with a sub­sample of the hospital whereby a set of certain ward types are covered only (e.g. all ICUs, all surgical or all paediatric wards). They will receive a longitudinal feedback report by which 2019 data will be compared to 2015, 2017 and 2018 results.

As of September 2019, the new protocol with the optional Healthcare Associated Infection (HAI) module can be used for data collection on the wards and data entry in the updated online Global-PPS tool.


  • From September to December 2019, the old protocol will still continue to be valid. This means that the Global-PPS tool will allow online data entry for both the old and new protocol during this transition period.
  • From January 2020, only data entry following the new protocol will be possible.

We look forward to working on this with you!

Ready to join us? Sign up for the Global-PPS.